Of course. this is all under the assumption that the Aβ hypothesis is true (which it likely isn’t), and that therapies which target Aβ actually lead to beneficial therapeutic responses Elephant: the hardest thing is watching somebody you love forget they love you (News Flash: they don’t, and they actually worsen the disease course). Back to the drawing board, stoners.
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I wouldn’t call this “my hypothesis” since it would be a disservice to the researchers that actually formulated it by performing and reading through numerous studies. Particularly phase 3 clinical trials where targeting Aβ was a complete failure. Actually, 2/3 of all drugs on the market are derived from living things Elephant: the hardest thing is watching somebody you love forget they love you (probably more at this point), and are in fact “natural.” Furthermore, just because something is “natural,” doesn’t mean that it’s necessarily good or bad for you. A drug (like THC) can be perfectly “natural” and be found in a pill form.
Cyanide and ricin are perfectly natural, and they could kill you. CRISPR-Cas9 is perfectly natural (it’s a bacterial immune system) and it can be used to edit DNA and could potentially save millions. I have nothing against people who use marijuana recreationally, and I’m very much against its illegalization. But, do keep in mind that just because a company is for profit, doesn’t make them “bad,” and last time I checked, dispensaries were for profit as well.
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Does this make all companies angels? Absolutely not. But please don’t pretend like these dispensaries and companies which sell marijuana. And its products wouldn’t be inclined to throw you under the bus for their benefit. Because at the end of the day, a company is a company no matter what they sell. Also, maybe don’t advertise online in front of millions of people. That you recreationally use something that’s listed as a Schedule I narcotic.
Actually not necessarily anecdotal. Of course, there is the famous nun autopsy study which suggested that people can have significant. Aβ accumulation and display no signs of dementia. But, there’s actually a good amount of phase III clinical data which shows that targeting and eliminating Aβ has been failure in patients. The most recent one was published in NEJM.